DDR1

DDR1
ساختارهای موجود PDB جستجوی هم‌ساخت‌شناسی: PDBe RCSB فهرست شناسه‌های PDB 3ZOS, 4AG4, 4BKJ, 4CKR, 5BVK, 5BVN, 5BVO, 5BVW, 5FDP
معین‌کننده‌ها
نام‌های دیگر	DDR1, CAK, CD167, DDR, EHGK2, MCK10, NEP, NTRK4, PTK3, PTK3A, RTK6, TRKE, discoidin domain receptor tyrosine kinase 1
شناسه‌های بیرونی	OMIM: 600408; MGI: 99216; HomoloGene: 68212; GeneCards: DDR1; OMA:ENSG00000137332، ENSG00000229767، ENSG00000230456، ENSG00000234078، ENSG00000204580، ENSG00000223680 DDR1 - orthologs
موقعیت ژن (انسان) کروموزوم کروموزوم ۶ (انسان) نوار 6p21.33 شروع 30,876,421 bp پایان 30,900,156 bp
موقعیت ژن (موش) کروموزوم کروموزوم ۱۷ (موش) نوار 17 B1|17 18.7 cM شروع 35,992,459 bp پایان 36,015,513 bp
الگوی گسترش RNA Bgee انسان موش (هم‌ساخت) بیشترین بیان در ventricular zone right uterine tube ganglionic eminence olfactory zone of nasal mucosa C1 segment minor salivary glands skin of abdomen mucosa of esophagus بیشترین بیان در Epithelium of choroid plexus retinal pigment epithelium conjunctival fornix Rostral migratory stream medial ganglionic eminence epithelium of stomach داده‌های بیشتر بیان BioGPS داده‌های بیشتر بیان
هستی‌شناسی ژن عملکرد ملکولی transferase activity nucleotide binding protein kinase activity collagen binding metal ion binding kinase activity پیوند پروتئینی transmembrane receptor protein tyrosine kinase activity protein tyrosine kinase collagen receptor activity protein tyrosine kinase activity ATP binding تیروزین کیناز گیرنده‌ای ترکیبات سلولی integral component of membrane membrane receptor complex پوسته یاخته integral component of plasma membrane extracellular region اگزوزوم extracellular space فرایند زیستی collagen-activated tyrosine kinase receptor signaling pathway branching involved in mammary gland duct morphogenesis فسفرگیری transmembrane receptor protein tyrosine kinase signaling pathway female pregnancy extracellular matrix organization ear development mammary gland alveolus development regulation of extracellular matrix disassembly smooth muscle cell migration smooth muscle cell-matrix adhesion regulation of cell-matrix adhesion protein phosphorylation چسبندگی سلولی regulation of cell growth peptidyl-tyrosine phosphorylation شیردهی wound healing, spreading of cells embryo implantation negative regulation of cell population proliferation peptidyl-tyrosine autophosphorylation protein autophosphorylation axon development neuron projection extension cell-matrix adhesion positive regulation of cell population proliferation دگرگونی یاخته‌ regulation of extracellular matrix organization منابع: آمیگو / کوئیک‌گو
هم‌ساخت‌شناسی گونه‌ها انسان موش Entrez 780 12305 Ensembl ENSG00000215522،ENSG00000137332،ENSG00000229767،ENSG00000230456،ENSG00000234078،ENSG00000204580،ENSG00000223680 ENSMUSG00000003534 UniProt Q08345 Q03146 RefSeq (mRNA) NM_001202521 NM_001202522 NM_001202523 NM_001297652 NM_001297653 NM_001297654 NM_001954 NM_013993 NM_013994 NM_001198831 NM_001198833 NM_007584 NM_172962 RefSeq (پروتئین) NP_001189450 NP_001189451 NP_001189452 NP_001284581 NP_001284582 NP_001284583 NP_001945 NP_054699 NP_054700 NP_001284583.1 NP_054699.2 NP_001185760 NP_001185762 NP_031610 NP_766550 موقعیت (UCSC) Chr 6: 30.88 – 30.9 Mb Chr 17: 35.99 – 36.02 Mb جستجوی PubMed
ویکی‌داده
مشاهده/ویرایش انسان مشاهده/ویرایش موش

خانواده گیرندهٔ دومین دیسکوئیدین، عضو ۱ (انگلیسی: Discoidin domain receptor family, member 1) که با نام CD167a هم شناخته می‌شود، یک پروتئین است که در انسان توسط ژن «DDR1» کُدگذاری می‌شود.

ژن یادشده بر روی بازوی کوتاه کروموزوم ۶ و در نزدیکی ژن‌های HLA-I قرار دارد.

منابع

• مشارکت‌کنندگان ویکی‌پدیا. «DDR1». در دانشنامهٔ ویکی‌پدیای انگلیسی، بازبینی‌شده در ۱۵ سپتامبر ۲۰۱۹.

برای مطالعهٔ بیشتر

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