PVR cell adhesion molecule (Q3648605)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P15151

Immunoglobulin-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P15151

immunoglobulin subtype, protein family

1 reference

Immunoglobulin V-set domain, protein family

1 reference

CD80-like, immunoglobulin C2-set, protein family

1 reference

immunoglobulin-like domain, protein family

1 reference

protein homodimerization activity

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

virus receptor activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

1 reference

8 April 2019

protein binding

4 references

8 April 2019

The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

8 April 2019

A secreted protein microarray platform for extracellular protein interaction discovery

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

8 April 2019

Recognition of nectin-2 by the natural killer cell receptor T cell immunoglobulin and ITIM domain (TIGIT).

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

signaling receptor binding

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15151&geneProductId=UniProtKB:P15151

1 reference

26 September 2017

cell adhesion molecule binding

1 reference

26 September 2017

Identification of PVR (CD155) and Nectin-2 (CD112) as cell surface ligands for the human DNAM-1 (CD226) activating molecule

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15151&geneProductId=UniProtKB:P15151

signaling receptor activity

cell adhesion molecule binding

1 reference

8 April 2019

The poliovirus receptor protein is produced both as membrane-bound and secreted forms

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

integral component of membrane

The poliovirus receptor protein is produced both as membrane-bound and secreted forms

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

8 April 2019

8 April 2019

Identification of PVR (CD155) and Nectin-2 (CD112) as cell surface ligands for the human DNAM-1 (CD226) activating molecule

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

1 reference

8 April 2019

focal adhesion

1 reference

26 September 2017

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15151&geneProductId=UniProtKB:P15151

integral component of plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15151&geneProductId=UniProtKB:P15151

1 reference

26 September 2017

extracellular region

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

1 reference

8 April 2019

cell surface

1 reference

8 April 2019

Mast cell costimulation by CD226/CD112 (DNAM-1/Nectin-2): a novel interface in the allergic process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

extracellular exosome

1 reference

26 September 2017

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15151&geneProductId=UniProtKB:P15151

extracellular space

1 reference

8 April 2019

The poliovirus receptor protein is produced both as membrane-bound and secreted forms

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

focal adhesion

HDA

1 reference

8 April 2019

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

HDA

biological process

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

cell recognition

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15151&geneProductId=UniProtKB:P15151

1 reference

26 September 2017

susceptibility to natural killer cell mediated cytotoxicity

1 reference

26 September 2017

Identification of PVR (CD155) and Nectin-2 (CD112) as cell surface ligands for the human DNAM-1 (CD226) activating molecule

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15151&geneProductId=UniProtKB:P15151

cell adhesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

1 reference

8 April 2019

positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target

1 reference

26 September 2017

Identification of PVR (CD155) and Nectin-2 (CD112) as cell surface ligands for the human DNAM-1 (CD226) activating molecule

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15151&geneProductId=UniProtKB:P15151

regulation of immune response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

1 reference

8 April 2019

viral entry into host cell

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

susceptibility to T cell mediated cytotoxicity

1 reference

26 September 2017

Functional characterization of DNAM-1 (CD226) interaction with its ligands PVR (CD155) and nectin-2 (PRR-2/CD112)

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15151&geneProductId=UniProtKB:P15151

viral process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

1 reference

8 April 2019

adherens junction organization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

1 reference

8 April 2019

positive regulation of natural killer cell mediated cytotoxicity

1 reference

8 April 2019

Expression of the DNAM-1 ligands, Nectin-2 (CD112) and poliovirus receptor (CD155), on dendritic cells: relevance for natural killer-dendritic cell interaction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

homophilic cell adhesion via plasma membrane adhesion molecules

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target

susceptibility to natural killer cell mediated cytotoxicity

susceptibility to T cell mediated cytotoxicity

Identifiers

MeSH descriptor ID

C066100

subject named as

poliovirus receptor

0 references

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

inferred by common MeSH mappings on source and on Wikidata

1 reference

UMLS 2023