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October 21st – 22nd, 2026 // Hyatt Regency Chicago

Developing OT Security Fundamentals While
Building Next-Gen Cyber Resilience

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October 21st – 22nd, 2026 // Hyatt Regency Chicago

Developing OT Security Fundamentals While Building Next-Gen Cyber Resilience

Register Now

ManuSec USA Celebrates Its 11th Edition in Chicago on October 21st-22nd 2026

Manufacturing is now the world’s most targeted industry. In the U.S., the threat is even more acute: manufacturers experience more ransomware incidents than the rest of the world combined, while production outages cost an average of $1.9 million per day. As operational and financial risks continue to rise, strengthening IT/OT security has become a business-critical priority.

Under the core theme of “Solidifying OT Security Fundamentals While Building Next-Gen Cyber Resilience,” the 2026 program moves past simple perimeter defenses to bridge the gap between fundamental cyber hygiene and advanced autonomous defense. By attending, security leaders from America’s Aerospace & Defense, Machinery, Electrical, Food & Beverage, Automotive, Metals, Chemical, Pharma, Transportation Equipment manufacturing industries & more will acquire the tactical frameworks necessary to ensure continuous, minimum viable operations even during an active breach.

Grounded in this urgent reality, the 11th annual ManuSec USA summit brings together 150+ senior manufacturing security leaders, plant managers, and C-level executives to the Hyatt Regency Chicago this October 21-22. This condensed, two-day program provides the definitive playbook for security executives to mitigate financial risk, satisfy strict underwriting audits and defend American manufacturing against new and evolving cyber threats.

Check out the event overview or quick-view agenda to learn more about this years key themes and innovative session formats.

Event Overview
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Highly
Recommend

The Must-attend Event for Manufacturing Security Experts

Agenda
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IT & OT
Security Experts

Connect with Key Players from Across the Industry

Attendees
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A-List
Speakers

Be Inspired by the Brightest
Minds in the Industry

Speakers
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End-User to Vendor
Ratio

Market Leading Solutions
in a User-Centered Platform

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View All Speakers
View All Board Members

Excellent event, the overlap between IT & OT information was really helpful, and I had a great experience networking and being introduced to products I didn't know.

Product Development Security ArchitectVisteon

Excellent event, the Qatalyst Team was amazing and we moved several appointments forward during the event. Great conference with great attendees and very relevant topics.

EVP ICS SolutionsDarktrace

The focus on manufacturing security was excellent, there was the right amount of content at the right pace. The networking during table discussions throughout the day were very valuable. I would absolutely recommend this event, it was excellent.

CISOSPX Corporation

The networking breaks during the ManuSec event have been fantastic, that's the quality time we've got to spend with our existing and potential customers, It's been invaluable. My perception of the attendees is rather impressive, the wide breadth of folks, their titles and responsibilities across their respective organizations is fantastic.

Security EngineerTripwire

Great topics, I especially enjoyed discussing how to identify trust boundaries and found every single topic approached on stage very relevant. The event was excelent, I love the format and the many networking opportunities as well. I will definitely attend again.

Security and Identity Platforms ManagerAshland Inc

Great conference with a really great turnout of relevant companies and contacts. Very well organized with a knowledgeable and helpful event staff.

Lead Solutions EngineerHoneywell / SCADAfence